
SIMO Database
Small Intestinal Multi-Omic Data
Spatially and temporally precise, our non-contaminated sampling methods provide microbiome data points comparable to industry gold-standard, endoscopy.
16s Genomics


PCoA plot demonstrating the degree of similarity between the 16s sequenced bacterial profiles, genus level.
Untargeted Metabolomics

Independent Samples

Metabolomic heatmap demonstrating stark differences in the metabolites of samples obtained from the SIMBA capsule as compared to fecal, and strong similarities compared to endoscopy. Samples are arranged horizontally.
Targeted Metabolomics


Stark differences in Short Chain Fatty Acids from different regions of the GI : Endoscopic aspirate from Duodenum; Capsule aspirate from the Jejenum/Ileum and Stool

Stark differences in Bile Acids from different regions of the GI : Endoscopic aspirate from Duodenum; Capsule aspirate from the Jejenum/Ileum and Stool

Baseline
Real Time Capture
Post-Ingestion
Capsules ingested with probiotic strains demonstrate the ability of the SIMBA capsule to capture in real-time the arrival of the specific strains to the small intestine.

SIMBA Gut
Microbiome
Fecal
Microbiome


Anaerobic Culture

Aspirate collected from the small intestine via the SIMBA capsule is anaerobically preserved and sealed at the collection site, enabling the isolation of novel strains.