SIMO Database
Small Intestinal Multi-Omic Data
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Spatially and temporally precise, our non-contaminated sampling methods provide microbiome data points comparable to industry gold-standard, endoscopy.
16s Genomics
PCoA plot demonstrating the degree of similarity between the 16s sequenced bacterial profiles, genus level.
Untargeted Metabolomics
Independent Samples
Metabolomic heatmap demonstrating stark differences in the metabolites of samples obtained from the SIMBA capsule as compared to fecal, and strong similarities compared to endoscopy. Samples are arranged horizontally.
Targeted Metabolomics
Stark differences in Short Chain Fatty Acids from different regions of the GI : Endoscopic aspirate from Duodenum; Capsule aspirate from the Jejenum/Ileum and Stool
Stark differences in Bile Acids from different regions of the GI : Endoscopic aspirate from Duodenum; Capsule aspirate from the Jejenum/Ileum and Stool
Baseline
Real Time Capture
Post-Ingestion
Capsules ingested with probiotic strains demonstrate the ability of the SIMBA capsule to capture in real-time the arrival of the specific strains to the small intestine.
SIMBA Gut
Microbiome
Fecal
Microbiome
Anaerobic Culture
Aspirate collected from the small intestine via the SIMBA capsule is anaerobically preserved and sealed at the collection site, enabling the isolation of novel strains.